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百奥赛图邀您共同探讨—生物医药研发的未来方向 - 实验动物

百奥赛图邀您共同探讨—生物医药研发的未来方向 - 实验动物

百奥赛图邀您共同探讨—生物医药研发的未来方向 - 实验动物

本次大会由Biocytogen和AcroBiosystem联合主办,围绕生物医药以及抗体药物的发现与发展,致力于为生物医药产业做出更多的贡献。 会议于美国时间2019年6月13日下午1-6点在波士顿召开,届时欢迎大家莅临参会。 Freetoattend,,focusingma:June13th,1:00PM-6:00PMLocation:ResidenceInnBostonCambridge,120Broadway,SixCambridgeCenter,Cambridge,MAConfirmedSpeakersChun-NanChenCEOandCSO,SingleCellTechnologyQingcongLinCEO,BiocytogenBostonCorpStephenGilliesCSO,LinkedUpBioscienceIncJohannaLahdenrantaDirectorofInVivoPharmacology,BicycleTherapeuticsXiaodongLiAssociateofPatentandIntellectualProperty,Choate,HallStewartLLPAgenda1:00PM-1:20PMRegistration1:20PM-1:30PMWelcomeRemark1:30PM-2:00PMIntroducingAbTheneum,AHighThroughputandData-richAntibodyDiscoveryPlatformbySingleCellTechnologyChun-NanChen,CEOandCSO,SingleCellTechnologyNamedafteraninstitutionofgreatknowledge,,wescreenthousandsofantibody-secretingcellsforbindingcharacteristicsandsequenceallthecellstoreturnnativeheavyandlightchainsequencepairtofindcross-reactivity,epitopespecificity,:00PM-2:30PMAcceleratingTherapeuticAntibodyCandidateDiscoveryusingBiocytogenHumanizedMouseModelsQingcongLin,CEO,BiocytogenBostonCorpThetraditionaltherapeuticantibodydiscoveryisalengthy,multi-stagedprocessfromhitgeneration,leadscreening,,Biocytogenhasgeneratedthirty+IOcheckpointhumanizedGEMM,enablingdirecttestingofanti-humanantibodi,ourproprietaryimmunodeficientB-NDGandseriesofB-NDGvariantmiceareexcellenthostforengraftmentofhumanPBMCandCD34+hematopoieticstemc,wehavegeneratedRenMabmice,byintroducingthecompletehumanheavychainandlightchainV(D),whereweconsiderablyshortenedthehittoleadprocessbyconductinghigh-throughputinvivoefficacy-:30PM-3:00PMHumanizedMiceforStudiesofImmunocytokineMonoandCombi-therapiesStephenGillies,CSO,LinkedUpBioscienceIncAntibody-cytokinefusionproteins(immunocytokinesorIC)targetthetumormicroenvironmentwheretheystimulateacascadeofimmuneresponsesbasedontheirinteractionwithresidenttumor,stromaandinfiltratinglymphocytes,s,thebestwayistousemurinecytokinesinsyngeneictumormodelsortousehumanizedNOGmicewiththeall,incollaborationwithJacksonLabsandtheUniversityofTuebingen,wedevelopedmodelsinwhichCD34+humanhematopoieticstemcellswereadoptivelytransferredintoirradiatedNOGmiceandgivenweeklydosesoflong-lastingIL7(Fc-IL7).ThisresultedinmicewithhighnumbersofhumanB,NKandTcellsthatquicklydevelopdiverseTCRrepertoiresandhaves,NHS-IL12,containstwomoleculesofspecies-specifichumanIL12andtargetsDNAthatisreleasedintothenecroticregionsofallsolidtumors,:00PM-3:30PMCoffeeBreakandNetworking3:30PM-4:00PMActivationofCD137UsingMultivalentandTumorTargetedBicyclicPeptidesJohannaLahdenranta,DirectorofInVivoPharmacology,BicycleTherapeutics4:00PM-4:30PMPatentPortfolioDevelopmentforBiologicProductsXiaodongLi,AssociateofPatentandIntellectualProperty,Choate,HallStewartLLPBiologicalproductsar,Xiaodongwilldiscusshowtousedifferenttypesofpatentfilingsandclaimstoprovidelayeredprote:30PM6:00PMDinnerReception(Lightdinnerwillbeprovided)Toregisterforthesymposium,pleaseorgoto。

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